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        ODS MEDICAL LESSONS LEARNED
            PERSONNEL CATEGORY
            PERSONNEL ISSUE NO. 15 Pyridostigmine Side Effects
            (SGHR ITEM NO. 232)
        
        DISCUSSION: Cases of side effects were reported for personnel taking
        pyridostigmine tablets. Empirical evidence (i.e.; qualitative clinical
        experience during the deployment) suggests that side effects did occur but were
        generally mild and not incapacitating. Some evidence suggests that individuals
        stopped taking the drug early or a variety of reasons.
        RECOMMENDATIONS: Question of risks v. benefits of use should be re-addressed
        by appropriate pharmacology and toxicology experts at the tri-service level
        employing scientific prospective analysis.
        
        ACTIONS REQUIRED: Evaluate risks v. benefits of pyridostigmine tablets ,
        regarding future use.
        
        ACTIONS COMPLETED: Noted. Notwithstanding side effects, pyridostigmine
        tablets will be used in future contingencies where the threat warrants until a
        more effective substitute is developed.
        STATUS: Closed.
        

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