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Research Topics
Health and Human Services Department of Defense Veterans Affairs Health and Human Services Gulf War Information Department of Defense Gulf War Information Veterans Affairs Gulf War Information Home Home Advanced Search Glossary FAQs Site Map Contact Us
 Research Topics    |    Major Focus Areas
Research Topics
ACCIDENTS & INJURIES
BONE, JOINT & MUSCLE
BRAIN & NERVOUS
CANCER
CARDIOVASCULAR
CHEMICAL WARFARE
DIGESTIVE HEALTH
ENVIRONMENTAL & OCCUPATIONAL HEALTH
FAMILY HEALTH
GENERAL HEALTH & PHYSICAL SYMPTOMS
GENETIC STUDIES
HEALTH RESEARCH OF ALLIED FORCES
IMMUNE/BLOOD SYSTEM
INFECTIONS
LUNG & RESPIRATORY
MENTAL HEALTH
MILITARY WORKING DOGS
MORTALITY/DEATH
REPRODUCTIVE HEALTH/OUTCOMES
SLEEP DISORDER
Treatment
VACCINES & PROTECTIVE MEDICATIONS
General Health & Physical Symptoms
General
Project Summary

Title: Epidemiologic Studies of Morbidity Among Gulf War Veterans: A Search for Etiologic Agents and Risk Factors; Study 2: A Comparative Study of Hospitalizations among Active-Duty Personnel Who Participated in the Gulf War and Similar Personnel Who Did Not
Synopsis: The study compares Gulf War-era deployed veterans' risk for hospitalization to that of non-deployed veterans.
Overall Project Objective: To determine if the risk of hospitalization is the same for Gulf War veterans (GWV) and nondeployed veterans (NDV).
Status/Results to Date: In general, Gulf War veterans postwar hospitalization data were very similar to that of their nondeployed peers. There was little evidence of unexplained increased postwar hospitalization morbidity associated with Gulf War service.
Project:DoD-1B
Agency:Department Of Defense
Location:Naval Health Research Center
P.I. Name:Greg Gray, CAPT, USN
Research Type:Epidemiology
Research Focus:Symptoms & General Health
Focus Category:General Health & Physical Symptoms
Status:Complete
Study Start Date:July 01,1994
Estimated Completion Date:October 01,1998
Specific Aims: Screen Department of Defense (DoD) hospitalizations for association with Gulf War deployment, 2) Identify specific diseases or disease groups that merit further study.
Methodology: This is a tri-service, retrospective cohort study using hospital discharge records from all DoD facilities. The study population consists of 2 groups: nearly all active-duty personnel who were deployed to the Persian Gulf any time between 1 August 1990 and 31 July 1991 (N= 578,492). Hospitalization records for the subjects were supplied by the DoD Manpower Data Center from all military hospitals. Each discharge diagnosis was classified into 1 of the 14 major classifications of disease and injuries as defined by ICD-9-CM. Multivariate logistic regression was used to compute odds ratios for hospitalization of GWV relative to EV for all 14 categories. A Cox proportional hazards model is being used to compare risks of hospitalizations among a subset of these categories.
Most Recent Publications:

Gray G, Smith TC, Kang HK, Knoke JD. Are Gulf War veterans Suffering War-Related Illnesses? Federal and Civilian Hospitalizations Examined, June 1991 To December 1994. American Journal of Epidemiology, 151(1):63-71. Jan 2000. Abstract

Smith TC, Heller JM, Hooper TI, Gackstetter GD, Gray G. Are Gulf War veterans experiencing illness due to exposure to smoke from Kuwaiti oil well fires? Examination of Department of Defense hospitalization data. American Journal of Epidemiology, 155(10):908-917. May 2002. Abstract

Smith TC. Calculating the Probability of Hospitalization risk after possible exposure to Iraqi chemical munitions destruction during the Persian Gulf War. Conference on Federally Sponsored Gulf War Veterans Illnesses Research, Jun 1998. Miscellaneous

Gray GC, Knoke JD, Berg SW, Wignall FS, Barrett-Connor E. Counterpoint: Responding to suppositions and misunderstandings. American Journal of Epidemiology, Vol 148, No.4, 328-33, No abstract available, Aug 1998. Article

Knoke JD, Gray GC. Hospitalizations after the Gulf War-Reply To K.M. Leisure et al. Emerging Infectious Diseases, 4(4):709, Oct 1998. Abstract

Knoke JD, Gray GC. Hospitalizations for Unexplained Illnesses Among U.S. Veterans of the Persian Gulf War. Emerging Infectious Diseases, Apr-Jun;4(2):211-9, 1998. Abstract

Smith TC, Gray GC, Knoke JD. Is systemic lupus erythematosus, amyotrophic lateral sclerosis, or fibromyalgia associated with Persian Gulf War service? An examination of Department of Denfense hospitalization data. American Journal of Epidemiology, 151(11):1053-9. Jun 2000. Abstract

Nushi B. Polychotomous Logistic Regression and the Creation of Odds Ratios and Confidence Intervals Using the SAS PROC CATMOD. Proceedings of the 7th Annual Western Users of SAS Software, Regional Users Group Conference, Oct 20-22, 1999. Miscellaneous

Dlugosz LJ, Hocter WJ, Kaiser KS, Knoke JD, Heller JM, Hamid NA, Reed RJ, Kendler KS, Gray GC. Risk factors for mental disorder hospitalization after the Persian Gulf War: US Armed Forces, June 1, 1991 - September 30, 1993. J Clin Epidemiol, 52 (12): 1267-78, Dec 1999. Abstract

Knoke JD, Gray GC, Garland FC. Testicular cancer with Persian Gulf War service. Epidemiology, 9(6):648-53, Nov 1998. Abstract

Gray GC, Smith TC, Knoke JD, Heller JM. The postwar hospitalization experience of Gulf War veterans possibly exposed to chemical munitions destruction at Khamisiyah, Iraq. American Journal of Epidemiology, 150 (5) 532-40, Sep 1999. Abstract

Gray GC, Coate BD, Anderson CM, Kang HK, Berg SW, Wignall FS, Knoke JD, Barrett-Connor E. The postwar hospitalization experience of U.S. Veterans of the Persian Gulf War. New England Journal of Medicine, 335:(20)1505-13, Nov 1996. Abstract