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File: 082696_doc1_476.txt
Page: 476
Total Pages: 652

           o ~.commend Septra ordoxycycline, on. tablet daily
           o Prophylaxti will not be e+~ective 1+ organism `has
             been ~enetically ma ipulated to render it res~stant
           o Renistance against  or+loxacin/cipro~loxacin less
             likely, but may be better to hold this in reserve
             +or treatment

      o  Vaccination

           o Would not recommen~j currently avai~able vaccine;
             not very e++ecttve and not likely to be e++.ctive
             under BW conditions

      o  Procurement

           o Need ~dditional oral Septra-DS and doxycycline
               -  ~OQ tabs o+ each +or 100 individuals,
                  assuming a ~ day exposure
                    -  Could be either Septra-DS or doxycycline
                       but will need to allow +or allergies
           o Need nor+loxacin ofl cipro+lo}cactn in the +teld or
             readily available ~or treatment +ailures, and
             possibly prophylaxis
               -  Minimum o~ tOO 400 mg nor+loxacin tablets +or
                  too individuals +or one course 0+ treatment,
                  or 1200 2~O m~ cipro+loxacin tablets (600
                  ~OO m~ tablets)

      0  Lo~istics

           o No comments

      o  ~xporta~le trainin~ program

           o ~imple handout should su+~ice

      o  Other critical issues

           o Non.

UNtTS T~R~~T~D ~OR PROTECTION

      o  No recommendationsi this is an operational/intelligence
         dec 1 Si On

OTHER CRITIC~L ~SSUEB

      o  None

RECOMMENO~T I ON~

      o  Protect +ood/water sources ~rom delib~rate contamination
      o  Us. prophylactic antibiotics 1+ exposure is tmmine~t or
         con+ I rmed

                                 5


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